Chapter 7 - The Extraction

The process of donating peripheral blood stem cells is not simple. It is not a quick pinch of a needle and an adhesive bandage.
For four days prior to the procedure, I had to inject myself twice daily with filgrastim—a medication that stimulated my bone marrow to hyper-produce stem cells and spill them out into my bloodstream.
By the third day, my skeleton felt as though it were made of pressurized lead. My hips, my sternum, my lower back throbbed with a deep, aching pressure that made sitting down an ordeal.
I didn't take pain medication. Every time a dull, heavy pulse throbbed in my hip bones, I thought of Lily. I thought of the bone marrow biopsies she had endured with tears streaming silently down her small cheeks, whispering, *“I’m being brave, Mommy. I’m being brave.”*
This was my turn to be brave. Not for Daniel. For the debt the universe owed her.
On the fifth day, I was admitted to the apheresis unit on the third floor of the cancer center.
The machine was massive, a whirring apparatus of plastic tubing, centrifuges, and anticoagulant bags. They inserted a large-bore catheter into the antecubital vein of my right arm, and another into my left. For six hours, my blood was drained from my body, spun at high speed to separate the microscopic harvest of CD34-positive stem cells, and then pumped back into my other arm, chilled and thinned.
Daniel was two floors above me, receiving the high-dose conditioning chemotherapy designed to wipe out his diseased bone marrow—and his immune system along with it.
If my cells did not engraft, he would die of a simple fungal infection within weeks.
At 4:00 PM, the apheresis nurse lifted the collection bag from the machine hook. It was heavy, containing nearly four hundred milliliters of cloudy, amber-tinted liquid that glowed faintly under the fluorescent lights.
"That is a stellar harvest, Clara," the nurse said, smiling through her mask. "Over nine million cells per kilogram. Your brother has a fighting chance."
I stared at the bag.
That fluid held the blueprint of my life. The genetic inheritance of our shared ancestors, purged of the cancer that was trying to extinguish him.
"Can you deliver a message with that?" I asked.
The nurse paused. "Officially, protocol discourages personal notes with transfusions. But unofficially... what do you want to say?"
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"Tell him," I whispered, closing my eyes as the cold saline flushed my veins, "that Lily built this bridge. He has to walk across it."
***